101 RRAMIREZ.pmd
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چکیده
101 l conocimiento de la dinámica de los ecosistemas forestales es fundamental para asegurar su adecuado aprovechamiento, pero dada la gran longevidad del componente arbóreo se requeriría de varias generaciones humanas para hacer el seguimiento debido basándose en un enfoque experimental. Una valiosa herramienta para su estudio la constituyen los modelos de simulación, de los cuales han sido desarrollados un gran número, desde
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Beyond the numbers: A uer-centered design apporach for personal reflective healthcare technolgies
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متن کاملA novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells
MicroRNA-101 (miR-101) is frequently downregulated in various cancers. To date, the regulatory networks of miR-101 remain obscure. In this study, we demonstrated that miR-101 was mainly transcribed from human miR-101-2 and mouse miR-101bgene loci. Subsequent analyses revealed that activator protein-1 (AP-1) directly binded to the -17.4 to -16.4 k region upstream of pre-miR-101-2 and activated t...
متن کاملThe miR-101/RUNX1 feedback regulatory loop modulates chemo-sensitivity and invasion in human lung cancer.
The deregulation of miR-101 has been implicated in multiple cancer types including lung cancer, but the exact role, mechanisms and how silencing of miR-101 remain elusive. Here we confirmed miR-101 downregulation in lung cancer cell lines and patient tissues. Restored miR-101 expression remarkably sensitized lung cancer cells to chemotherapy and inhibited invasion. Mechanistically, we indicated...
متن کاملMicroRNA-101 inhibits cell proliferation, invasion, and promotes apoptosis by regulating cyclooxygenase-2 in Hela cervical carcinoma cells.
AIM Although aberrant miRNA expression has been documented, altered miR-101 expression in cervical cancer and its carcinogenic effects and mechanisms remain unexplored. The aim of our study was to investigate the role of miR-101 alteration in cervical carcinogenesis. METHODS Expression of miR-101 was examined by quantitative real-time reverse transcriptase PCR (qRT-PCR) in Hela cells. After m...
متن کاملDown-regulated microRNA-101 in bladder transitional cell carcinoma is associated with poor prognosis
BACKGROUND Down-regulation of microRNA-101 (miR-101) expression has been linked to bladder transitional cell carcinoma (BTCC) development. However, the relationship between the expression of miR-101 in BTCC and a patient's prognosis has not yet been studied. Thus, we attempted to explore the correlation of miR-101 and clinicopathological factors of BTCC patients, and evaluate the impact of miR-...
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